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Passive transfer of experimental autoimmune myasthenia by lymph node cells in inbred guinea pigs
Passive transfer of experimental autoimmune myasthenia (EAM) was performed with lymph node cells from donor guinea pigs immunized with purified acetylcholine receptor (AChR) from Torpedo californica. Recipient animals revealed the same clinical signs and electromyographic patterns as observed in act...
Formato: | Texto |
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Lenguaje: | English |
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The Rockefeller University Press
1975
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2189911/ https://www.ncbi.nlm.nih.gov/pubmed/1165476 |
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collection | PubMed |
description | Passive transfer of experimental autoimmune myasthenia (EAM) was performed with lymph node cells from donor guinea pigs immunized with purified acetylcholine receptor (AChR) from Torpedo californica. Recipient animals revealed the same clinical signs and electromyographic patterns as observed in actively challenged animals. These phenomena are parallel to the clinical manifestations of the human disease myasthenia gravis, in which cellular response to AChR was recently demonstrated. |
format | Text |
id | pubmed-2189911 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 1975 |
publisher | The Rockefeller University Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-21899112008-04-17 Passive transfer of experimental autoimmune myasthenia by lymph node cells in inbred guinea pigs J Exp Med Articles Passive transfer of experimental autoimmune myasthenia (EAM) was performed with lymph node cells from donor guinea pigs immunized with purified acetylcholine receptor (AChR) from Torpedo californica. Recipient animals revealed the same clinical signs and electromyographic patterns as observed in actively challenged animals. These phenomena are parallel to the clinical manifestations of the human disease myasthenia gravis, in which cellular response to AChR was recently demonstrated. The Rockefeller University Press 1975-09-01 /pmc/articles/PMC2189911/ /pubmed/1165476 Text en This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/). |
spellingShingle | Articles Passive transfer of experimental autoimmune myasthenia by lymph node cells in inbred guinea pigs |
title | Passive transfer of experimental autoimmune myasthenia by lymph node cells in inbred guinea pigs |
title_full | Passive transfer of experimental autoimmune myasthenia by lymph node cells in inbred guinea pigs |
title_fullStr | Passive transfer of experimental autoimmune myasthenia by lymph node cells in inbred guinea pigs |
title_full_unstemmed | Passive transfer of experimental autoimmune myasthenia by lymph node cells in inbred guinea pigs |
title_short | Passive transfer of experimental autoimmune myasthenia by lymph node cells in inbred guinea pigs |
title_sort | passive transfer of experimental autoimmune myasthenia by lymph node cells in inbred guinea pigs |
topic | Articles |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2189911/ https://www.ncbi.nlm.nih.gov/pubmed/1165476 |