Detection of non-H2 antigen(s) which, like Ia antigens, are associated with the Fc receptor of B lymphocytes

Antibodies contained in an A/J anti-B10 antiserum, when tested on lymphocytes from B10.A mice, were shown to bind to both B and T cells and to inhibit the binding of Ig complexes to the Fc receptors of B lymphocytes. These antibodies could be removed by absorption with B10.D2 lymphocytes. Similar re...

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Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1975
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2189933/
https://www.ncbi.nlm.nih.gov/pubmed/1100765
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description Antibodies contained in an A/J anti-B10 antiserum, when tested on lymphocytes from B10.A mice, were shown to bind to both B and T cells and to inhibit the binding of Ig complexes to the Fc receptors of B lymphocytes. These antibodies could be removed by absorption with B10.D2 lymphocytes. Similar results were obtained with lymphocytes from two to six (B6A)F1 x A/J backcross mice which had H-2a/a genotype. These data indicate that alloantigens determined by at least one non-H- 2 locus are associated with or a part of Fc receptors. These antigens may be similar in structure and function to Ia antigens.
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spelling pubmed-21899332008-04-17 Detection of non-H2 antigen(s) which, like Ia antigens, are associated with the Fc receptor of B lymphocytes J Exp Med Articles Antibodies contained in an A/J anti-B10 antiserum, when tested on lymphocytes from B10.A mice, were shown to bind to both B and T cells and to inhibit the binding of Ig complexes to the Fc receptors of B lymphocytes. These antibodies could be removed by absorption with B10.D2 lymphocytes. Similar results were obtained with lymphocytes from two to six (B6A)F1 x A/J backcross mice which had H-2a/a genotype. These data indicate that alloantigens determined by at least one non-H- 2 locus are associated with or a part of Fc receptors. These antigens may be similar in structure and function to Ia antigens. The Rockefeller University Press 1975-09-01 /pmc/articles/PMC2189933/ /pubmed/1100765 Text en This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Articles
Detection of non-H2 antigen(s) which, like Ia antigens, are associated with the Fc receptor of B lymphocytes
title Detection of non-H2 antigen(s) which, like Ia antigens, are associated with the Fc receptor of B lymphocytes
title_full Detection of non-H2 antigen(s) which, like Ia antigens, are associated with the Fc receptor of B lymphocytes
title_fullStr Detection of non-H2 antigen(s) which, like Ia antigens, are associated with the Fc receptor of B lymphocytes
title_full_unstemmed Detection of non-H2 antigen(s) which, like Ia antigens, are associated with the Fc receptor of B lymphocytes
title_short Detection of non-H2 antigen(s) which, like Ia antigens, are associated with the Fc receptor of B lymphocytes
title_sort detection of non-h2 antigen(s) which, like ia antigens, are associated with the fc receptor of b lymphocytes
topic Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2189933/
https://www.ncbi.nlm.nih.gov/pubmed/1100765

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