A receptor for the third component of complement in the human renal glomerulus

In the course of studying the nature of mononuclear cellular infiltrates in tissue sections of human kidney it was noted that indicator sheep erythrocytes densely coated with the third component of complement (C3) specifically adhered to all of the glomeruli in the tissue sections. The deposition of...

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Detalles Bibliográficos
Autores principales: Gelfand, MC, Frank, MM, Green, I
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1975
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2189942/
https://www.ncbi.nlm.nih.gov/pubmed/1176888
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author Gelfand, MC
Frank, MM
Green, I
author_facet Gelfand, MC
Frank, MM
Green, I
author_sort Gelfand, MC
collection PubMed
description In the course of studying the nature of mononuclear cellular infiltrates in tissue sections of human kidney it was noted that indicator sheep erythrocytes densely coated with the third component of complement (C3) specifically adhered to all of the glomeruli in the tissue sections. The deposition of complement (C) within the glomerulus is a feature of many immunologically related renal diseases (1,2), yet the precise mechanism by which C is deposited remains unexplained. We feel that this observation, suggesting the presence of a receptor for C, is, therefore, of particular interest.
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spelling pubmed-21899422008-04-17 A receptor for the third component of complement in the human renal glomerulus Gelfand, MC Frank, MM Green, I J Exp Med Articles In the course of studying the nature of mononuclear cellular infiltrates in tissue sections of human kidney it was noted that indicator sheep erythrocytes densely coated with the third component of complement (C3) specifically adhered to all of the glomeruli in the tissue sections. The deposition of complement (C) within the glomerulus is a feature of many immunologically related renal diseases (1,2), yet the precise mechanism by which C is deposited remains unexplained. We feel that this observation, suggesting the presence of a receptor for C, is, therefore, of particular interest. The Rockefeller University Press 1975-10-01 /pmc/articles/PMC2189942/ /pubmed/1176888 Text en This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Articles
Gelfand, MC
Frank, MM
Green, I
A receptor for the third component of complement in the human renal glomerulus
title A receptor for the third component of complement in the human renal glomerulus
title_full A receptor for the third component of complement in the human renal glomerulus
title_fullStr A receptor for the third component of complement in the human renal glomerulus
title_full_unstemmed A receptor for the third component of complement in the human renal glomerulus
title_short A receptor for the third component of complement in the human renal glomerulus
title_sort receptor for the third component of complement in the human renal glomerulus
topic Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2189942/
https://www.ncbi.nlm.nih.gov/pubmed/1176888
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AT greeni receptorforthethirdcomponentofcomplementinthehumanrenalglomerulus

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