The occurrence of the HL-B alloantigens on the cells of unclassified acute lymphoblastic leukemias

Six cases of acute lymphoblastic leukemia were studied by a variety of T- and B-lymphocyte surface markers. Two appeared to represent T-cell leukemias with the lymphoblasts forming sheep erythrocyte rosettes. The other four lacked all the usual membrane markers. However, indirect immunofluorescence...

Descripción completa

Detalles Bibliográficos
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1975
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2189979/
https://www.ncbi.nlm.nih.gov/pubmed/1104744
_version_ 1782146741604188160
collection PubMed
description Six cases of acute lymphoblastic leukemia were studied by a variety of T- and B-lymphocyte surface markers. Two appeared to represent T-cell leukemias with the lymphoblasts forming sheep erythrocyte rosettes. The other four lacked all the usual membrane markers. However, indirect immunofluorescence with alloantisera detected the presence of the Ia- related HL-B antigens on the cells of the latter four cases; these antigens were absent in the first two cases. The primary association of the HL-B antigens with B cells raises the possibility that the positive group of cases are of B-cell lineage.
format Text
id pubmed-2189979
institution National Center for Biotechnology Information
language English
publishDate 1975
publisher The Rockefeller University Press
record_format MEDLINE/PubMed
spelling pubmed-21899792008-04-17 The occurrence of the HL-B alloantigens on the cells of unclassified acute lymphoblastic leukemias J Exp Med Articles Six cases of acute lymphoblastic leukemia were studied by a variety of T- and B-lymphocyte surface markers. Two appeared to represent T-cell leukemias with the lymphoblasts forming sheep erythrocyte rosettes. The other four lacked all the usual membrane markers. However, indirect immunofluorescence with alloantisera detected the presence of the Ia- related HL-B antigens on the cells of the latter four cases; these antigens were absent in the first two cases. The primary association of the HL-B antigens with B cells raises the possibility that the positive group of cases are of B-cell lineage. The Rockefeller University Press 1975-11-01 /pmc/articles/PMC2189979/ /pubmed/1104744 Text en This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Articles
The occurrence of the HL-B alloantigens on the cells of unclassified acute lymphoblastic leukemias
title The occurrence of the HL-B alloantigens on the cells of unclassified acute lymphoblastic leukemias
title_full The occurrence of the HL-B alloantigens on the cells of unclassified acute lymphoblastic leukemias
title_fullStr The occurrence of the HL-B alloantigens on the cells of unclassified acute lymphoblastic leukemias
title_full_unstemmed The occurrence of the HL-B alloantigens on the cells of unclassified acute lymphoblastic leukemias
title_short The occurrence of the HL-B alloantigens on the cells of unclassified acute lymphoblastic leukemias
title_sort occurrence of the hl-b alloantigens on the cells of unclassified acute lymphoblastic leukemias
topic Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2189979/
https://www.ncbi.nlm.nih.gov/pubmed/1104744

Ejemplares similares