Genetic control of cutaneous basophil hypersensitivity

CBH to DNP-GL could be elicited only in responder guinea pigs which possess the genetic ability to develop classic delayed type hypersensitivity to DNP-PLL, the response to which is governed by the same gene. Since the defect in nonresponder animals seems to reside at the level of their T cells and...

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Detalles Bibliográficos
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1976
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2190090/
https://www.ncbi.nlm.nih.gov/pubmed/1081582
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description CBH to DNP-GL could be elicited only in responder guinea pigs which possess the genetic ability to develop classic delayed type hypersensitivity to DNP-PLL, the response to which is governed by the same gene. Since the defect in nonresponder animals seems to reside at the level of their T cells and not B cells, these results lend support to the contention that CBH, as well as DH, is dependent on and probably mediated by T cells.
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spelling pubmed-21900902008-04-17 Genetic control of cutaneous basophil hypersensitivity J Exp Med Articles CBH to DNP-GL could be elicited only in responder guinea pigs which possess the genetic ability to develop classic delayed type hypersensitivity to DNP-PLL, the response to which is governed by the same gene. Since the defect in nonresponder animals seems to reside at the level of their T cells and not B cells, these results lend support to the contention that CBH, as well as DH, is dependent on and probably mediated by T cells. The Rockefeller University Press 1976-01-01 /pmc/articles/PMC2190090/ /pubmed/1081582 Text en This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Articles
Genetic control of cutaneous basophil hypersensitivity
title Genetic control of cutaneous basophil hypersensitivity
title_full Genetic control of cutaneous basophil hypersensitivity
title_fullStr Genetic control of cutaneous basophil hypersensitivity
title_full_unstemmed Genetic control of cutaneous basophil hypersensitivity
title_short Genetic control of cutaneous basophil hypersensitivity
title_sort genetic control of cutaneous basophil hypersensitivity
topic Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2190090/
https://www.ncbi.nlm.nih.gov/pubmed/1081582

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