Studies on the role of the host immune response in recovery from Friend virus leukemia. II. Cell-mediated immunity

Congenic mouse strains differing only at genes within the H-2 complex were found to have virus-specific cytotoxic effector cells in their spleens during or after recovery from Friend leukemia virus-induced splenomegaly. These effector cells were theta-positive T lymphocytes which functioned in vitro...

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Detalles Bibliográficos
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1976
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2190102/
https://www.ncbi.nlm.nih.gov/pubmed/1081583
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description Congenic mouse strains differing only at genes within the H-2 complex were found to have virus-specific cytotoxic effector cells in their spleens during or after recovery from Friend leukemia virus-induced splenomegaly. These effector cells were theta-positive T lymphocytes which functioned in vitro without help or inhibition by B lymphocytes or glass-adherent cells. The antigenic specificities recognized by the effector cells were viral-induced cellular antigens apparently different from those identified by serological techniques.
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spelling pubmed-21901022008-04-17 Studies on the role of the host immune response in recovery from Friend virus leukemia. II. Cell-mediated immunity J Exp Med Articles Congenic mouse strains differing only at genes within the H-2 complex were found to have virus-specific cytotoxic effector cells in their spleens during or after recovery from Friend leukemia virus-induced splenomegaly. These effector cells were theta-positive T lymphocytes which functioned in vitro without help or inhibition by B lymphocytes or glass-adherent cells. The antigenic specificities recognized by the effector cells were viral-induced cellular antigens apparently different from those identified by serological techniques. The Rockefeller University Press 1976-01-01 /pmc/articles/PMC2190102/ /pubmed/1081583 Text en This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Articles
Studies on the role of the host immune response in recovery from Friend virus leukemia. II. Cell-mediated immunity
title Studies on the role of the host immune response in recovery from Friend virus leukemia. II. Cell-mediated immunity
title_full Studies on the role of the host immune response in recovery from Friend virus leukemia. II. Cell-mediated immunity
title_fullStr Studies on the role of the host immune response in recovery from Friend virus leukemia. II. Cell-mediated immunity
title_full_unstemmed Studies on the role of the host immune response in recovery from Friend virus leukemia. II. Cell-mediated immunity
title_short Studies on the role of the host immune response in recovery from Friend virus leukemia. II. Cell-mediated immunity
title_sort studies on the role of the host immune response in recovery from friend virus leukemia. ii. cell-mediated immunity
topic Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2190102/
https://www.ncbi.nlm.nih.gov/pubmed/1081583

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