Amyloid-related serum protein SAA in endotoxin-induced amyloidosis of the mink

The concentration of the amyloid AA-related serum protein (SAA) was markedly increased after endotoxin injections in mink, mouse, rabbit, and man. It was particularly studied during the development of endotoxin-induced amyloidosis of the mink. Protein SAA was markedly elevated in all mink 24 h after...

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Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1976
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2190143/
https://www.ncbi.nlm.nih.gov/pubmed/765426
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collection PubMed
description The concentration of the amyloid AA-related serum protein (SAA) was markedly increased after endotoxin injections in mink, mouse, rabbit, and man. It was particularly studied during the development of endotoxin-induced amyloidosis of the mink. Protein SAA was markedly elevated in all mink 24 h after the first endotoxin injection but had fallen to relatively low levels before the onset of amyloidosis at about 4 wk. These results are consistent with SAA being a circulating precursor of the amyloid fibril protein, AA. However, both proteins may be derived by proteolysis from a common precursor.
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spelling pubmed-21901432008-04-17 Amyloid-related serum protein SAA in endotoxin-induced amyloidosis of the mink J Exp Med Articles The concentration of the amyloid AA-related serum protein (SAA) was markedly increased after endotoxin injections in mink, mouse, rabbit, and man. It was particularly studied during the development of endotoxin-induced amyloidosis of the mink. Protein SAA was markedly elevated in all mink 24 h after the first endotoxin injection but had fallen to relatively low levels before the onset of amyloidosis at about 4 wk. These results are consistent with SAA being a circulating precursor of the amyloid fibril protein, AA. However, both proteins may be derived by proteolysis from a common precursor. The Rockefeller University Press 1976-03-01 /pmc/articles/PMC2190143/ /pubmed/765426 Text en This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Articles
Amyloid-related serum protein SAA in endotoxin-induced amyloidosis of the mink
title Amyloid-related serum protein SAA in endotoxin-induced amyloidosis of the mink
title_full Amyloid-related serum protein SAA in endotoxin-induced amyloidosis of the mink
title_fullStr Amyloid-related serum protein SAA in endotoxin-induced amyloidosis of the mink
title_full_unstemmed Amyloid-related serum protein SAA in endotoxin-induced amyloidosis of the mink
title_short Amyloid-related serum protein SAA in endotoxin-induced amyloidosis of the mink
title_sort amyloid-related serum protein saa in endotoxin-induced amyloidosis of the mink
topic Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2190143/
https://www.ncbi.nlm.nih.gov/pubmed/765426

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