Differences between pig tissues in the expression of major transplantation antigens: possible relevance for organ allografts

Evidence is presented that there are differences between pig liver and kidney parenchymal cells in the expression of major histocompatibility complex antigens. Analogues of I-region antigens of the mouse are detectable on kidney cells and some peripheral blood leukocytes (PBL) but not on liver, plat...

Descripción completa

Detalles Bibliográficos
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1976
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2190169/
https://www.ncbi.nlm.nih.gov/pubmed/1255116
_version_ 1782146766219509760
collection PubMed
description Evidence is presented that there are differences between pig liver and kidney parenchymal cells in the expression of major histocompatibility complex antigens. Analogues of I-region antigens of the mouse are detectable on kidney cells and some peripheral blood leukocytes (PBL) but not on liver, platelets, and other PBL. Such differences between liver and kidney may explain (a) the fate of these organs as allografts and (b) the donor-specific protection of kidney by liver. Other antigens peculiar to skin and kidney have been detected but require further characterization.
format Text
id pubmed-2190169
institution National Center for Biotechnology Information
language English
publishDate 1976
publisher The Rockefeller University Press
record_format MEDLINE/PubMed
spelling pubmed-21901692008-04-17 Differences between pig tissues in the expression of major transplantation antigens: possible relevance for organ allografts J Exp Med Articles Evidence is presented that there are differences between pig liver and kidney parenchymal cells in the expression of major histocompatibility complex antigens. Analogues of I-region antigens of the mouse are detectable on kidney cells and some peripheral blood leukocytes (PBL) but not on liver, platelets, and other PBL. Such differences between liver and kidney may explain (a) the fate of these organs as allografts and (b) the donor-specific protection of kidney by liver. Other antigens peculiar to skin and kidney have been detected but require further characterization. The Rockefeller University Press 1976-04-01 /pmc/articles/PMC2190169/ /pubmed/1255116 Text en This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Articles
Differences between pig tissues in the expression of major transplantation antigens: possible relevance for organ allografts
title Differences between pig tissues in the expression of major transplantation antigens: possible relevance for organ allografts
title_full Differences between pig tissues in the expression of major transplantation antigens: possible relevance for organ allografts
title_fullStr Differences between pig tissues in the expression of major transplantation antigens: possible relevance for organ allografts
title_full_unstemmed Differences between pig tissues in the expression of major transplantation antigens: possible relevance for organ allografts
title_short Differences between pig tissues in the expression of major transplantation antigens: possible relevance for organ allografts
title_sort differences between pig tissues in the expression of major transplantation antigens: possible relevance for organ allografts
topic Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2190169/
https://www.ncbi.nlm.nih.gov/pubmed/1255116

Ejemplares similares