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The HLA system in the families of patients with juvenile diabetes mellitus
The HLA and Bf genotypes were determined in 10 families with one or more children with JDM. A statistically significant association was found between HLA-D-identity and the chance to present JDM within a sibship. No such association was detectable with the SD antigens. A highly significant increase...
Formato: | Texto |
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Lenguaje: | English |
Publicado: |
The Rockefeller University Press
1976
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2190181/ https://www.ncbi.nlm.nih.gov/pubmed/1262788 |
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collection | PubMed |
description | The HLA and Bf genotypes were determined in 10 families with one or more children with JDM. A statistically significant association was found between HLA-D-identity and the chance to present JDM within a sibship. No such association was detectable with the SD antigens. A highly significant increase in the frequency of intra-HLA recombination was also found in these families. |
format | Text |
id | pubmed-2190181 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 1976 |
publisher | The Rockefeller University Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-21901812008-04-17 The HLA system in the families of patients with juvenile diabetes mellitus J Exp Med Articles The HLA and Bf genotypes were determined in 10 families with one or more children with JDM. A statistically significant association was found between HLA-D-identity and the chance to present JDM within a sibship. No such association was detectable with the SD antigens. A highly significant increase in the frequency of intra-HLA recombination was also found in these families. The Rockefeller University Press 1976-05-01 /pmc/articles/PMC2190181/ /pubmed/1262788 Text en This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/). |
spellingShingle | Articles The HLA system in the families of patients with juvenile diabetes mellitus |
title | The HLA system in the families of patients with juvenile diabetes mellitus |
title_full | The HLA system in the families of patients with juvenile diabetes mellitus |
title_fullStr | The HLA system in the families of patients with juvenile diabetes mellitus |
title_full_unstemmed | The HLA system in the families of patients with juvenile diabetes mellitus |
title_short | The HLA system in the families of patients with juvenile diabetes mellitus |
title_sort | hla system in the families of patients with juvenile diabetes mellitus |
topic | Articles |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2190181/ https://www.ncbi.nlm.nih.gov/pubmed/1262788 |