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The HLA system in the families of patients with juvenile diabetes mellitus

The HLA and Bf genotypes were determined in 10 families with one or more children with JDM. A statistically significant association was found between HLA-D-identity and the chance to present JDM within a sibship. No such association was detectable with the SD antigens. A highly significant increase...

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Detalles Bibliográficos
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1976
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2190181/
https://www.ncbi.nlm.nih.gov/pubmed/1262788
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description The HLA and Bf genotypes were determined in 10 families with one or more children with JDM. A statistically significant association was found between HLA-D-identity and the chance to present JDM within a sibship. No such association was detectable with the SD antigens. A highly significant increase in the frequency of intra-HLA recombination was also found in these families.
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spelling pubmed-21901812008-04-17 The HLA system in the families of patients with juvenile diabetes mellitus J Exp Med Articles The HLA and Bf genotypes were determined in 10 families with one or more children with JDM. A statistically significant association was found between HLA-D-identity and the chance to present JDM within a sibship. No such association was detectable with the SD antigens. A highly significant increase in the frequency of intra-HLA recombination was also found in these families. The Rockefeller University Press 1976-05-01 /pmc/articles/PMC2190181/ /pubmed/1262788 Text en This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Articles
The HLA system in the families of patients with juvenile diabetes mellitus
title The HLA system in the families of patients with juvenile diabetes mellitus
title_full The HLA system in the families of patients with juvenile diabetes mellitus
title_fullStr The HLA system in the families of patients with juvenile diabetes mellitus
title_full_unstemmed The HLA system in the families of patients with juvenile diabetes mellitus
title_short The HLA system in the families of patients with juvenile diabetes mellitus
title_sort hla system in the families of patients with juvenile diabetes mellitus
topic Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2190181/
https://www.ncbi.nlm.nih.gov/pubmed/1262788