Cargando…
Growth of B-lymphocytes clones in semisolid culture is mitogen dependent
A substance which was mitogenic for murine B lymphocytes in the presence of 2-mercaptoethanol was isolated from agar. Stimulating activity of this material was stable to proteolysis or protein denaturants but was destroyed by periodate treatment. Agar-derived mitogen stimulation was distinct from th...
Formato: | Texto |
---|---|
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
1976
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2190186/ https://www.ncbi.nlm.nih.gov/pubmed/1083421 |
_version_ | 1782146770222972928 |
---|---|
collection | PubMed |
description | A substance which was mitogenic for murine B lymphocytes in the presence of 2-mercaptoethanol was isolated from agar. Stimulating activity of this material was stable to proteolysis or protein denaturants but was destroyed by periodate treatment. Agar-derived mitogen stimulation was distinct from that obtained with dextran sulfate or lipopolysaccharide and may define different populations of B lymphocytes. |
format | Text |
id | pubmed-2190186 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 1976 |
publisher | The Rockefeller University Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-21901862008-04-17 Growth of B-lymphocytes clones in semisolid culture is mitogen dependent J Exp Med Articles A substance which was mitogenic for murine B lymphocytes in the presence of 2-mercaptoethanol was isolated from agar. Stimulating activity of this material was stable to proteolysis or protein denaturants but was destroyed by periodate treatment. Agar-derived mitogen stimulation was distinct from that obtained with dextran sulfate or lipopolysaccharide and may define different populations of B lymphocytes. The Rockefeller University Press 1976-05-01 /pmc/articles/PMC2190186/ /pubmed/1083421 Text en This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/). |
spellingShingle | Articles Growth of B-lymphocytes clones in semisolid culture is mitogen dependent |
title | Growth of B-lymphocytes clones in semisolid culture is mitogen dependent |
title_full | Growth of B-lymphocytes clones in semisolid culture is mitogen dependent |
title_fullStr | Growth of B-lymphocytes clones in semisolid culture is mitogen dependent |
title_full_unstemmed | Growth of B-lymphocytes clones in semisolid culture is mitogen dependent |
title_short | Growth of B-lymphocytes clones in semisolid culture is mitogen dependent |
title_sort | growth of b-lymphocytes clones in semisolid culture is mitogen dependent |
topic | Articles |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2190186/ https://www.ncbi.nlm.nih.gov/pubmed/1083421 |