Antigen-induced co-capping of IgM and IgD-like receptors on murine B cells

Double fluorescence studies indicated that most mature lymphocytes of 11-52-wk-old mice possess both IgM and IgD-like surface immunoglobulins, while spleen cells from neonatal mice possess surface IgM only. These molecules cap independently with class-specific antisera, but co-cap when capping is in...

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Detalles Bibliográficos
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1976
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2190395/
https://www.ncbi.nlm.nih.gov/pubmed/822118
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collection PubMed
description Double fluorescence studies indicated that most mature lymphocytes of 11-52-wk-old mice possess both IgM and IgD-like surface immunoglobulins, while spleen cells from neonatal mice possess surface IgM only. These molecules cap independently with class-specific antisera, but co-cap when capping is induced by antigen. It is proposed that the two heavy chains on individual lymphocytes possess similar or identical antigen-combining sites.
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spelling pubmed-21903952008-04-17 Antigen-induced co-capping of IgM and IgD-like receptors on murine B cells J Exp Med Articles Double fluorescence studies indicated that most mature lymphocytes of 11-52-wk-old mice possess both IgM and IgD-like surface immunoglobulins, while spleen cells from neonatal mice possess surface IgM only. These molecules cap independently with class-specific antisera, but co-cap when capping is induced by antigen. It is proposed that the two heavy chains on individual lymphocytes possess similar or identical antigen-combining sites. The Rockefeller University Press 1976-09-01 /pmc/articles/PMC2190395/ /pubmed/822118 Text en This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Articles
Antigen-induced co-capping of IgM and IgD-like receptors on murine B cells
title Antigen-induced co-capping of IgM and IgD-like receptors on murine B cells
title_full Antigen-induced co-capping of IgM and IgD-like receptors on murine B cells
title_fullStr Antigen-induced co-capping of IgM and IgD-like receptors on murine B cells
title_full_unstemmed Antigen-induced co-capping of IgM and IgD-like receptors on murine B cells
title_short Antigen-induced co-capping of IgM and IgD-like receptors on murine B cells
title_sort antigen-induced co-capping of igm and igd-like receptors on murine b cells
topic Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2190395/
https://www.ncbi.nlm.nih.gov/pubmed/822118

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