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Secretion of Ia antigens by a subpopulation of T cells which are Ly-1+, Ly-2-, and Ia-
It was found that Ia antignes are rapidly secreted by a subpopulation of splenic T lymphocytes which are nonadherent and which express the surface phenotype Ly-1+, Ly-2-, and Ia-. Secretion of the Ia antigens was a metabolically active process which was inhibited by sodium azide and by Pactamycin, a...
| Formato: | Texto |
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| Lenguaje: | English |
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The Rockefeller University Press
1976
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2190400/ https://www.ncbi.nlm.nih.gov/pubmed/1085342 |
| Sumario: | It was found that Ia antignes are rapidly secreted by a subpopulation of splenic T lymphocytes which are nonadherent and which express the surface phenotype Ly-1+, Ly-2-, and Ia-. Secretion of the Ia antigens was a metabolically active process which was inhibited by sodium azide and by Pactamycin, an inhibitor of protein synthesis. |
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