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Macrophage plasminogen activator: induction by asbestos is blocked by anti-inflammatory steroids

Intraperitoneal injection of asbestos fibres into mice induces the formation of exudates containing macrophages that produce plasminogen activator. Like-wise, in vitro addition of asbestos to macrophage cultures stimulates plasminogen activator secretion; the synthesis and secretion of lysozyme and...

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Detalles Bibliográficos
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1976
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2190481/
https://www.ncbi.nlm.nih.gov/pubmed/1003109
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description Intraperitoneal injection of asbestos fibres into mice induces the formation of exudates containing macrophages that produce plasminogen activator. Like-wise, in vitro addition of asbestos to macrophage cultures stimulates plasminogen activator secretion; the synthesis and secretion of lysozyme and lysosomal enzymes are not changed under these conditions. The enhanced secretion of plasminogen activator by macrophages exposed to asbestos is suppressed by low concentrations of anti-inflammatory steroids.
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spelling pubmed-21904812008-04-17 Macrophage plasminogen activator: induction by asbestos is blocked by anti-inflammatory steroids J Exp Med Articles Intraperitoneal injection of asbestos fibres into mice induces the formation of exudates containing macrophages that produce plasminogen activator. Like-wise, in vitro addition of asbestos to macrophage cultures stimulates plasminogen activator secretion; the synthesis and secretion of lysozyme and lysosomal enzymes are not changed under these conditions. The enhanced secretion of plasminogen activator by macrophages exposed to asbestos is suppressed by low concentrations of anti-inflammatory steroids. The Rockefeller University Press 1976-12-01 /pmc/articles/PMC2190481/ /pubmed/1003109 Text en This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Articles
Macrophage plasminogen activator: induction by asbestos is blocked by anti-inflammatory steroids
title Macrophage plasminogen activator: induction by asbestos is blocked by anti-inflammatory steroids
title_full Macrophage plasminogen activator: induction by asbestos is blocked by anti-inflammatory steroids
title_fullStr Macrophage plasminogen activator: induction by asbestos is blocked by anti-inflammatory steroids
title_full_unstemmed Macrophage plasminogen activator: induction by asbestos is blocked by anti-inflammatory steroids
title_short Macrophage plasminogen activator: induction by asbestos is blocked by anti-inflammatory steroids
title_sort macrophage plasminogen activator: induction by asbestos is blocked by anti-inflammatory steroids
topic Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2190481/
https://www.ncbi.nlm.nih.gov/pubmed/1003109