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Demonstration of an antibody-mediated tolerance state and its effect on antibody affinity
We have described a model of immunological tolerance induced, in adult mice, by a single injection of a moderate dose of a hapten-protein conjugate. The data suggest that the mechanism of this tolerance state is the production of small amounts of high affinity antibody in response to the tolerance-i...
Formato: | Texto |
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Lenguaje: | English |
Publicado: |
The Rockefeller University Press
1975
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2190525/ https://www.ncbi.nlm.nih.gov/pubmed/1089745 |