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Differential Roles for α(M)β(2) Integrin Clustering or Activation in the Control of Apoptosis via Regulation of Akt and ERK Survival Mechanisms
The role of integrins in leukocyte apoptosis is unclear, some studies suggest enhancement, others inhibition. We have found that β(2)-integrin engagement on neutrophils can either inhibit or enhance apoptosis depending on the activation state of the integrin and the presence of proapoptotic stimuli....
| Autores principales: | , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
2000
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2190581/ https://www.ncbi.nlm.nih.gov/pubmed/11121444 |