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Characterization of the G-quadruplexes in the duplex nuclease hypersensitive element of the PDGF-A promoter and modulation of PDGF-A promoter activity by TMPyP4

The proximal 5′-flanking region of the human platelet-derived growth factor A (PDGF-A) promoter contains one nuclease hypersensitive element (NHE) that is critical for PDGF-A gene transcription. On the basis of circular dichroism (CD) and electrophoretic mobility shift assay (EMSA), we have shown th...

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Detalles Bibliográficos
Autores principales:	Qin, Yong, Rezler, Evonne M., Gokhale, Vijay, Sun, Daekyu, Hurley, Laurence H.
Formato:	Texto
Lenguaje:	English
Publicado:	Oxford University Press 2007
Materias:	Molecular Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2190695/ https://www.ncbi.nlm.nih.gov/pubmed/17984069 http://dx.doi.org/10.1093/nar/gkm538

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