Oxidative DNA damage in mild cognitive impairment and late-stage Alzheimer's disease

Increasing evidence supports a role for oxidative DNA damage in aging and several neurodegenerative diseases including Alzheimer's disease (AD). Attack of DNA by reactive oxygen species (ROS), particularly hydroxyl radicals, can lead to strand breaks, DNA–DNA and DNA–protein cross-linking, and...

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Detalles Bibliográficos
Autores principales: Lovell, Mark A., Markesbery, William R.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2007
Materias:
Survey and Summary
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2190704/
https://www.ncbi.nlm.nih.gov/pubmed/17947327
http://dx.doi.org/10.1093/nar/gkm821

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2190704/
https://www.ncbi.nlm.nih.gov/pubmed/17947327
http://dx.doi.org/10.1093/nar/gkm821

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