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Oxidative DNA damage in mild cognitive impairment and late-stage Alzheimer's disease
Increasing evidence supports a role for oxidative DNA damage in aging and several neurodegenerative diseases including Alzheimer's disease (AD). Attack of DNA by reactive oxygen species (ROS), particularly hydroxyl radicals, can lead to strand breaks, DNA–DNA and DNA–protein cross-linking, and...
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2007
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2190704/ https://www.ncbi.nlm.nih.gov/pubmed/17947327 http://dx.doi.org/10.1093/nar/gkm821 |