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Characterization of DNA-binding activity of Zα domains from poxviruses and the importance of the β-wing regions in converting B-DNA to Z-DNA

The E3L gene is essential for pathogenesis in vaccinia virus. The E3L gene product consists of an N-terminal Zα domain and a C-terminal double-stranded RNA (dsRNA) binding domain; the left-handed Z-DNA-binding activity of the Zα domain of E3L is required for viral pathogenicity in mice. E3L is highl...

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Detalles Bibliográficos
Autores principales:	Van Quyen, Dong, Ha, Sung Chul, Lowenhaupt, Ky, Rich, Alexander, Kim, Kyeong Kyu, Kim, Yang-Gyun
Formato:	Texto
Lenguaje:	English
Publicado:	Oxford University Press 2007
Materias:	Molecular Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2190711/ https://www.ncbi.nlm.nih.gov/pubmed/17984076 http://dx.doi.org/10.1093/nar/gkm748

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