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Saccharomyces cerevisiae Ebs1p is a putative ortholog of human Smg7 and promotes nonsense-mediated mRNA decay

The Smg proteins Smg5, Smg6 and Smg7 are involved in nonsense-mediated RNA decay (NMD) in metazoans, but no orthologs have been found in the budding yeast Saccharomyces cerevisiae. Sequence alignments reveal that yeast Ebs1p is similar in structure to the human Smg5-7, with highest homology to Smg7....

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Detalles Bibliográficos
Autores principales:	Luke, Brian, Azzalin, Claus M., Hug, Nele, Deplazes, Anna, Peter, Matthias, Lingner, Joachim
Formato:	Texto
Lenguaje:	English
Publicado:	Oxford University Press 2007
Materias:	RNA
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2190716/ https://www.ncbi.nlm.nih.gov/pubmed/17984081 http://dx.doi.org/10.1093/nar/gkm912

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