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Human premature aging, DNA repair and RecQ helicases
Genomic instability leads to mutations, cellular dysfunction and aberrant phenotypes at the tissue and organism levels. A number of mechanisms have evolved to cope with endogenous or exogenous stress to prevent chromosomal instability and maintain cellular homeostasis. DNA helicases play important r...
Autores principales: | Brosh, Robert M., Bohr, Vilhelm A. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2007
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2190726/ https://www.ncbi.nlm.nih.gov/pubmed/18006573 http://dx.doi.org/10.1093/nar/gkm1008 |
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