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Clonal mutations in primary human glial tumors: evidence in support of the mutator hypothesis
BACKGROUND: A verifiable consequence of the mutator hypothesis is that even low grade neoplasms would accumulate a large number of mutations that do not influence the tumor phenotype (clonal mutations). In this study, we have attempted to quantify the number of clonal mutations in primary human glio...
Autores principales: | Misra, Anjan, Chattopadhyay, Parthaprasad, Chosdol, Kunzang, Sarkar, Chitra, Mahapatra, Ashok K, Sinha, Subrata |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2007
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2190769/ https://www.ncbi.nlm.nih.gov/pubmed/17925012 http://dx.doi.org/10.1186/1471-2407-7-190 |
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