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The Generation R Study Biobank: a resource for epidemiological studies in children and their parents

The Generation R Study is a population-based prospective cohort study from fetal life until young adulthood. The study is designed to identify early environmental and genetic causes of normal and abnormal growth, development and health from fetal life until young adulthood. In total, 9,778 mothers w...

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Autores principales: Jaddoe, Vincent W. V., Bakker, Rachel, van Duijn, Cock M., van der Heijden, Albert J., Lindemans, Jan, Mackenbach, Johan P., Moll, Henriëtte A., Steegers, Eric A. P., Tiemeier, Henning, Uitterlinden, Andre G., Verhulst, Frank C., Hofman, Albert
Formato: Texto
Lenguaje:English
Publicado: Springer Netherlands 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2190786/
https://www.ncbi.nlm.nih.gov/pubmed/18095172
http://dx.doi.org/10.1007/s10654-007-9209-z
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author Jaddoe, Vincent W. V.
Bakker, Rachel
van Duijn, Cock M.
van der Heijden, Albert J.
Lindemans, Jan
Mackenbach, Johan P.
Moll, Henriëtte A.
Steegers, Eric A. P.
Tiemeier, Henning
Uitterlinden, Andre G.
Verhulst, Frank C.
Hofman, Albert
author_facet Jaddoe, Vincent W. V.
Bakker, Rachel
van Duijn, Cock M.
van der Heijden, Albert J.
Lindemans, Jan
Mackenbach, Johan P.
Moll, Henriëtte A.
Steegers, Eric A. P.
Tiemeier, Henning
Uitterlinden, Andre G.
Verhulst, Frank C.
Hofman, Albert
author_sort Jaddoe, Vincent W. V.
collection PubMed
description The Generation R Study is a population-based prospective cohort study from fetal life until young adulthood. The study is designed to identify early environmental and genetic causes of normal and abnormal growth, development and health from fetal life until young adulthood. In total, 9,778 mothers were enrolled in the study. Prenatal and postnatal data collection is conducted by physical examinations, questionnaires, interviews, ultrasound examinations and biological samples. Major efforts have been conducted for collecting biological specimens including DNA, blood for phenotypes and urine samples. In this paper, the collection, processing and storage of these biological specimens are described. Together with detailed phenotype measurements, these biological specimens form a unique resource for epidemiological studies focused on environmental exposures, genetic determinants and their interactions in relation to growth, health and development from fetal life onwards.
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spelling pubmed-21907862008-01-12 The Generation R Study Biobank: a resource for epidemiological studies in children and their parents Jaddoe, Vincent W. V. Bakker, Rachel van Duijn, Cock M. van der Heijden, Albert J. Lindemans, Jan Mackenbach, Johan P. Moll, Henriëtte A. Steegers, Eric A. P. Tiemeier, Henning Uitterlinden, Andre G. Verhulst, Frank C. Hofman, Albert Eur J Epidemiol Developmental Epidemiology The Generation R Study is a population-based prospective cohort study from fetal life until young adulthood. The study is designed to identify early environmental and genetic causes of normal and abnormal growth, development and health from fetal life until young adulthood. In total, 9,778 mothers were enrolled in the study. Prenatal and postnatal data collection is conducted by physical examinations, questionnaires, interviews, ultrasound examinations and biological samples. Major efforts have been conducted for collecting biological specimens including DNA, blood for phenotypes and urine samples. In this paper, the collection, processing and storage of these biological specimens are described. Together with detailed phenotype measurements, these biological specimens form a unique resource for epidemiological studies focused on environmental exposures, genetic determinants and their interactions in relation to growth, health and development from fetal life onwards. Springer Netherlands 2007-12-19 2007-12 /pmc/articles/PMC2190786/ /pubmed/18095172 http://dx.doi.org/10.1007/s10654-007-9209-z Text en © The Author(s) 2007
spellingShingle Developmental Epidemiology
Jaddoe, Vincent W. V.
Bakker, Rachel
van Duijn, Cock M.
van der Heijden, Albert J.
Lindemans, Jan
Mackenbach, Johan P.
Moll, Henriëtte A.
Steegers, Eric A. P.
Tiemeier, Henning
Uitterlinden, Andre G.
Verhulst, Frank C.
Hofman, Albert
The Generation R Study Biobank: a resource for epidemiological studies in children and their parents
title The Generation R Study Biobank: a resource for epidemiological studies in children and their parents
title_full The Generation R Study Biobank: a resource for epidemiological studies in children and their parents
title_fullStr The Generation R Study Biobank: a resource for epidemiological studies in children and their parents
title_full_unstemmed The Generation R Study Biobank: a resource for epidemiological studies in children and their parents
title_short The Generation R Study Biobank: a resource for epidemiological studies in children and their parents
title_sort generation r study biobank: a resource for epidemiological studies in children and their parents
topic Developmental Epidemiology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2190786/
https://www.ncbi.nlm.nih.gov/pubmed/18095172
http://dx.doi.org/10.1007/s10654-007-9209-z
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