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Homozygous scid/scid;beige/beige mice have low levels of spontaneous or neonatal T cell-induced B cell generation
The autosomal recessive scid mutation results in defective immunoglobulin and T cell receptor gene rearrangement. The scid mutation occurred in the allotype congenic C.B-17 line, and up to 25% of C.B-17 scid mice spontaneously produce both T cells and immunoglobulin, a phenotype known as "leaky...
| Formato: | Texto |
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| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
1993
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2190863/ https://www.ncbi.nlm.nih.gov/pubmed/8418200 |