The life span of naive alpha/beta T cells in secondary lymphoid organs

We have determined the life span of naive CD4-8+ T cells in T cell receptor transgenic mice. We find that such cells do not divide in secondary lymphoid organs in both normal euthymic mice and T cell- deficient mice. By both continuous labeling and by chasing pulse- labeled cells, we find that the m...

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Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1993
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2190982/
https://www.ncbi.nlm.nih.gov/pubmed/8459219
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description We have determined the life span of naive CD4-8+ T cells in T cell receptor transgenic mice. We find that such cells do not divide in secondary lymphoid organs in both normal euthymic mice and T cell- deficient mice. By both continuous labeling and by chasing pulse- labeled cells, we find that the minimum life span of the naive T cells is in the order of 8 wk.
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spelling pubmed-21909822008-04-16 The life span of naive alpha/beta T cells in secondary lymphoid organs J Exp Med Articles We have determined the life span of naive CD4-8+ T cells in T cell receptor transgenic mice. We find that such cells do not divide in secondary lymphoid organs in both normal euthymic mice and T cell- deficient mice. By both continuous labeling and by chasing pulse- labeled cells, we find that the minimum life span of the naive T cells is in the order of 8 wk. The Rockefeller University Press 1993-04-01 /pmc/articles/PMC2190982/ /pubmed/8459219 Text en This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Articles
The life span of naive alpha/beta T cells in secondary lymphoid organs
title The life span of naive alpha/beta T cells in secondary lymphoid organs
title_full The life span of naive alpha/beta T cells in secondary lymphoid organs
title_fullStr The life span of naive alpha/beta T cells in secondary lymphoid organs
title_full_unstemmed The life span of naive alpha/beta T cells in secondary lymphoid organs
title_short The life span of naive alpha/beta T cells in secondary lymphoid organs
title_sort life span of naive alpha/beta t cells in secondary lymphoid organs
topic Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2190982/
https://www.ncbi.nlm.nih.gov/pubmed/8459219

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