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CD28-B7 interactions allow the induction of CD8+ cytotoxic T lymphocytes in the absence of exogenous help

The activation requirements for the generation of CD8+ cytotoxic T cells (CTL) are poorly understood. Here we demonstrate that in the absence of exogenous help, a CD28-B7 interaction is necessary and sufficient for generation of class I major histocompatibility complex- specific CTL. Costimulation i...

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Detalles Bibliográficos
Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 1993
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2191062/ https://www.ncbi.nlm.nih.gov/pubmed/7684435

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