Cargando…
Thymic epithelial cells provide unique signals for positive selection of CD4+CD8+ thymocytes in vitro
Using a novel system that supports positive selection in vitro, we have investigated the cellular requirements for this process by testing the ability of individual thymic and nonthymic stromal cell types to support the maturation of CD4+CD8+ thymocytes into CD4+ or CD8+ T cells. We show that thymic...
Formato: | Texto |
---|---|
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
1994
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2191508/ https://www.ncbi.nlm.nih.gov/pubmed/7910843 |
Ejemplares similares
-
T cell receptor-mediated signaling events in CD4+CD8+ thymocytes undergoing thymic selection: requirement of calcineurin activation for thymic positive selection but not negative selection
Publicado: (1995) -
Intermediate steps in positive selection: differentiation of CD4+8int TCRint thymocytes into CD4-8+TCRhi thymocytes
Publicado: (1995) -
Thymic Atrophy and Apoptosis of CD4(+)CD8(+) Thymocytes in the Cuprizone Model of Multiple Sclerosis
por: Solti, Izabella, et al.
Publicado: (2015) -
Maturation and migration of murine CD4 single positive thymocytes and thymic emigrants
por: Xu, Xi, et al.
Publicado: (2014) -
The Molecular Signature Underlying the Thymic Migration and Maturation of TCRαβ(+)CD4(+)CD8(-) Thymocytes
por: Teng, Fei, et al.
Publicado: (2011)