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Allele specificity of structural requirement for peptides bound to HLA- DRB1*0405 and -DRB1*0406 complexes: implication for the HLA-associated susceptibility to methimazole-induced insulin autoimmune syndrome
Self-peptides bound to HLA-DR4 (DRA-DRB1*0405 complex) were eluted from the purified DR4 complex, fractionated on reverse-phase HPLC, and subjected to NH2-terminal sequencing. Seven independent sequences were obtained, and all putative peptides synthesized bound to DRB1*0405 as well as DRB1*0406 com...
| Formato: | Texto |
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| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
1994
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2191632/ https://www.ncbi.nlm.nih.gov/pubmed/8064238 |