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Dysregulation of interleukin 4, interleukin 5, and interferon gamma gene expression in steroid-resistant asthma

In steroid-resistant (SR) asthma, there is a lack of clinical responsiveness to oral prednisone. Previous studies indicate that this may be explained by the effect of the combination of interleukin 2 (IL- 2) and IL-4 on glucocorticoid receptor binding affinity. By contrast, steroid-sensitive (SS) as...

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Detalles Bibliográficos
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1995
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2191836/
https://www.ncbi.nlm.nih.gov/pubmed/7807013