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Genetic requirement for Ras in the transformation of fibroblasts and hematopoietic cells by the Bcr-Abl oncogene
To determine the functional importance of Ras in transformation by Abl oncogenes, we used a genetic approach to measure the effect of impaired Ras activity on the ability of Bcr-Abl or v-Abl to transform cells. Expression of the catalytic domain of the GTPase activating protein for Ras (Gap C termin...
| Formato: | Texto |
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| Lenguaje: | English |
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The Rockefeller University Press
1995
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2191855/ https://www.ncbi.nlm.nih.gov/pubmed/7807010 |