Cargando…

Normal T lymphocytes can express two different T cell receptor beta chains: implications for the mechanism of allelic exclusion

We have examined the extent of allelic exclusion at the T cell receptor (TCR) beta locus using monoclonal antibodies specific for V beta products. A small proportion (approximately 1%) of human peripheral blood T cells express two V beta as determined by flow cytometric analysis, isolation of repres...

Descripción completa

Detalles Bibliográficos
Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 1995
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2191970/ https://www.ncbi.nlm.nih.gov/pubmed/7699339

Ejemplares similares

Allelic exclusion at DNA rearrangement level is required to prevent coexpression of two distinct T cell receptor beta genes
Publicado: (1991)

Lack of Allelic Exclusion in B Cell Chronic Lymphocytic Leukemia
por: Rassenti, Laura Z., et al.
Publicado: (1997)

Extended Duration of DH–JH Rearrangement in Immunoglobulin Heavy Chain Transgenic Mice: Implications for Regulation of Allelic Exclusion
por: Chang, Yung, et al.
Publicado: (1999)

Dual T cell receptor beta chain expression on human T lymphocytes
Publicado: (1995)

CLASS, SUBCLASS, AND ALLELIC EXCLUSION OF MEMBRANE-BOUND Ig OF HUMAN B LYMPHOCYTES
por: Fröland, S. S., et al.
Publicado: (1972)

The cytoplasmic domains of immunoglobulin (Ig) alpha and Ig beta can independently induce the precursor B cell transition and allelic exclusion
Publicado: (1995)

Characterization of the T‐cell receptor beta chain repertoire in tumor‐infiltrating lymphocytes
por: Nakanishi, Katsumi, et al.
Publicado: (2016)

Allelic Exclusion of TCR α-Chains upon Severe Restriction of Vα Repertoire
por: Rybakin, Vasily, et al.
Publicado: (2014)

Editorial: Mechanisms of Lymphocyte Exclusion in the Tumor Microenvironment
por: van de Ven, Rieneke, et al.
Publicado: (2022)

Pre-B and B cells in rabbits. Ontogeny and allelic exclusion of kappa light chain genes
Publicado: (1978)

Epigenetic Regulation of Monoallelic Rearrangement (Allelic Exclusion) of Antigen Receptor Genes
por: Levin-Klein, Rena, et al.
Publicado: (2014)

Jane Skok: Choreography of allelic exclusion
por: Bashyam, Hema
Publicado: (2008)

Allelic exclusion of the immunoglobulin heavy chain locus is independent of its nuclear localization in mature B cells
por: Holwerda, Sjoerd J. B., et al.
Publicado: (2013)

Receptor Revision of Immunoglobulin Heavy Chain Variable Region Genes in Normal Human B Lymphocytes
por: Wilson, Patrick C., et al.
Publicado: (2000)

Endocytosis of interleukin 2 receptors in human T lymphocytes: distinct intracellular localization and fate of the receptor alpha, beta, and gamma chains
Publicado: (1995)

T cell receptor genes in a series of class I major histocompatibility complex-restricted cytotoxic T lymphocyte clones specific for a Plasmodium berghei nonapeptide: implications for T cell allelic exclusion and antigen-specific repertoire
Publicado: (1991)

T cell receptor beta chain gene rearrangements in lymphoproliferative disorders of large granular lymphocytes/natural killer cells
Publicado: (1985)

Immunoglobulin Heavy Chain Exclusion in the Shark
por: Malecek, Karolina, et al.
Publicado: (2008)

Gene correction in the evolution of the T cell receptor beta chain
Publicado: (1986)

HLA Allele Associations and V-Beta T-Lymphocyte Expansions in Patients With Psoriasis, Harboring Toxin-Producing Staphylococcus aureus
por: Ajib, Rola, et al.
Publicado: (2005)

Novel Method for Analysis of Allele Specific Expression in Triploid Oryzias latipes Reveals Consistent Pattern of Allele Exclusion
por: Garcia, Tzintzuni I., et al.
Publicado: (2014)

Rat T cell responses to superantigens. II. Allelic differences in V beta 8.2 and V beta 8.5 beta chains determine responsiveness to staphylococcal enterotoxin B and mouse mammary tumor virus-encoded products
Publicado: (1994)

Lack of gene rearrangement and mRNA expression of the beta chain of the T cell receptor in spontaneous rat large granular lymphocyte leukemia lines
Publicado: (1985)

Murine T cell receptor beta chain is encoded on chromosome 6
Publicado: (1984)

Transcriptional regulation of the mu-delta heavy chain locus in normal murine B lymphocytes
Publicado: (1984)

Allelic exclusion in transgenic mice carrying mutant human IgM genes
Publicado: (1988)

Pericyte-specific expression of PDGF beta receptor in mouse models with normal and deficient PDGF beta receptor signaling
por: Winkler, Ethan A, et al.
Publicado: (2010)

Expression and rearrangement of the alpha, beta, and gamma chain genes of the T cell receptor in cloned murine large granular lymphocyte lines. No correlation with the cytotoxic spectrum
Publicado: (1986)

Activated human T lymphocytes express MHC class I heavy chains not associated with beta 2-microglobulin
Publicado: (1990)

Transforming growth factor-beta 1 modulates beta 1 and beta 5 integrin receptors and induces the de novo expression of the alpha v beta 6 heterodimer in normal human keratinocytes: implications for wound healing
Publicado: (1995)

Identification and characterization of new murine T cell receptor beta chain variable region (V beta) genes
Publicado: (1989)

Distribution of dominant T cell receptor beta chains in human intestinal mucosa
Publicado: (1994)

A role for the IgH intronic enhancer Eμ in enforcing allelic exclusion
por: Li, Fubin, et al.
Publicado: (2009)

Allelic Exclusion in pTα-deficient Mice: No Evidence for Cell Surface Expression of Two T Cell Receptor (TCR)-β Chains, but Less Efficient Inhibition of Endogeneous Vβ→ (D)Jβ Rearrangements in the Presence of a Functional TCR-β Transgene
por: Krotkova, Anna, et al.
Publicado: (1997)

Allelic Exclusion of the T Cell Receptor β Locus Requires the Sh2 Domain–Containing Leukocyte Protein (Slp)-76 Adaptor Protein
por: Aifantis, Iannis, et al.
Publicado: (1999)

Regions of the T cell receptor alpha and beta chains that are responsible for interactions with CD3
Publicado: (1991)

Regions of the T cell receptor alpha and beta chains that are responsible for interactions with CD3
Publicado: (1991)

Induction of interleukin 2 receptor beta chain expression by self- recognition in the thymus
Publicado: (1994)

Sequences and diversity of human T cell receptor beta chain variable region genes
Publicado: (1986)

Fc-receptors, Ia-antigens, and immunoglobulin on normal and activated mouse T lymphocytes
Publicado: (1975)

Cannot write session to /tmp/vufind_sessions/sess_mkmd40fkcmhtvh156igku11hr3