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Bax and Bak Coalesce into Novel Mitochondria-Associated Clusters during Apoptosis
Bax is a member of the Bcl-2 family of proteins known to regulate mitochondria-dependent programmed cell death. Early in apoptosis, Bax translocates from the cytosol to the mitochondrial membrane. We have identified by confocal and electron microscopy a novel step in the Bax proapoptotic mechanism i...
Autores principales: | Nechushtan, Amotz, Smith, Carolyn L., Lamensdorf, Itschak, Yoon, Soo-Han, Youle, Richard J. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2001
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2192024/ https://www.ncbi.nlm.nih.gov/pubmed/11402069 |
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