Subdomain-Specific Localization of Climp-63 (P63) in the Endoplasmic Reticulum Is Mediated by Its Luminal α-Helical Segment

The microtubule-binding integral 63 kD cytoskeleton-linking membrane protein (CLIMP-63; former name, p63) of the rough endoplasmic reticulum (ER) is excluded from the nuclear envelope. We studied the mechanism underlying this ER subdomain–specific localization by mutagenesis and structural analysis....

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Detalles Bibliográficos
Autores principales: Klopfenstein, Dieter R., Klumperman, Judith, Lustig, Ariel, Kammerer, Richard A., Oorschot, Viola, Hauri, Hans-Peter
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2001
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2192027/
https://www.ncbi.nlm.nih.gov/pubmed/11402071

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