Serca1 Truncated Proteins Unable to Pump Calcium Reduce the Endoplasmic Reticulum Calcium Concentration and Induce Apoptosis

By pumping calcium from the cytosol to the ER, sarco/endoplasmic reticulum calcium ATPases (SERCAs) play a major role in the control of calcium signaling. We describe two SERCA1 splice variants (S1Ts) characterized by exon 4 and/or exon 11 splicing, encoding COOH terminally truncated proteins, havin...

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Detalles Bibliográficos
Autores principales: Chami, Mounia, Gozuacik, Devrim, Lagorce, David, Brini, Marisa, Falson, Pierre, Peaucellier, Gérard, Pinton, Paolo, Lecoeur, Hervé, Gougeon, Marie-Lyse, le Maire, Marc, Rizzuto, Rosario, Bréchot, Christian, Paterlini-Bréchot, Patrizia
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2001
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2192035/
https://www.ncbi.nlm.nih.gov/pubmed/11402072

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