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HIVgp120 activates autoreactive CD4-specific T cell responses by unveiling of hidden CD4 peptides during processing
T cells are made tolerant only to those self-peptides that are presented in sufficient amounts by antigen-presenting cells. They ignore cryptic self-determinants, such as either those not generated by processing machinery or generated in insufficient amounts. It is anticipated that mechanisms that e...
| Formato: | Texto |
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| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
1995
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2192056/ https://www.ncbi.nlm.nih.gov/pubmed/7760011 |