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Structural requirements regulate endoproteolytic release of the L- selectin (CD62L) adhesion receptor from the cell surface of leukocytes
L-selectin mediates leukocyte rolling on vascular endothelium at sites of inflammation and lymphocyte migration to peripheral lymph nodes. L- selectin is rapidly shed from the cell surface after leukocyte activation by a proteolytic mechanism that cleaves the receptor in a membrane proximal extracel...
| Formato: | Texto |
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| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
1995
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2192142/ https://www.ncbi.nlm.nih.gov/pubmed/7543141 |