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The interleukin-1 beta-converting enzyme (ICE) is localized on the external cell surface membranes and in the cytoplasmic ground substance of human monocytes by immuno-electron microscopy
Interleukin-1 beta (IL-1 beta)-converting enzyme (ICE) is a novel cysteine protease that cleaves the 31-kD inactive cytoplasmic IL-1 beta precursor into active extracellular 17-kD IL-1 beta. The ICE gene product is a 45-kD proenzyme that requires proteolytic processing to activate ICE. Active ICE is...
| Formato: | Texto |
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| Lenguaje: | English |
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The Rockefeller University Press
1995
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2192189/ https://www.ncbi.nlm.nih.gov/pubmed/7595215 |