A Central Role for the Armadillo Protein Plakoglobin in the Autoimmune Disease Pemphigus Vulgaris

In pemphigus vulgaris (PV), autoantibody binding to desmoglein (Dsg) 3 induces loss of intercellular adhesion in skin and mucous membranes. Two hypotheses are currently favored to explain the underlying molecular mechanisms: (a) disruption of adhesion through steric hindrance, and (b) interference o...

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Detalles Bibliográficos
Autores principales: Caldelari, Reto, de Bruin, Alain, Baumann, Dominique, Suter, Maja M., Bierkamp, Christiane, Balmer, Vreni, Müller, Eliane
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2001
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2192383/
https://www.ncbi.nlm.nih.gov/pubmed/11352942

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