Cargando…
CD40L-deficient mice show deficits in antiviral immunity and have an impaired memory CD8+ CTL response
The ligand for CD40 (CD40L) is expressed on the surface of activated CD4+ T cells and its role in T-B cell collaborations and thymus- dependent humoral immunity is well established. Recently, by generating CD40L-knockout mice, we have confirmed its previously described role in humoral immunity and d...
Formato: | Texto |
---|---|
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
1996
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2192549/ https://www.ncbi.nlm.nih.gov/pubmed/8642323 |
Ejemplares similares
-
Overcoming CD4 deficiency to induce long-lived memory CD8(+ )CTL
por: Oh, SangKon, et al.
Publicado: (2006) -
CD40-deficient, Influenza-specific CD8 Memory T Cells Develop and Function Normally in a CD40-sufficient Environment
por: Lee, Byung O., et al.
Publicado: (2003) -
Role of antigen, CD8, and cytotoxic T lymphocyte (CTL) avidity in high dose antigen induction of apoptosis of effector CTL
Publicado: (1996) -
Detuning CD8 T cells: down-regulation of CD8 expression, tetramer binding, and response during CTL activation
por: Xiao, Zhengguo, et al.
Publicado: (2007) -
CD40 Activation Rescues Antiviral CD8(+) T Cells from PD-1-Mediated Exhaustion
por: Isogawa, Masanori, et al.
Publicado: (2013)