Cargando…

Positive selection is not required for thymic maturation of transgenic gamma delta T cells

Previously published reports describing thymic differentiation in two TCR gamma delta transgenic mouse models have suggested that gamma delta T cells require MHC-mediated positive selection to reach full maturity. Recent studies indicate that recognition of antigen by mature gamma delta T cells is n...

Descripción completa

Detalles Bibliográficos
Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 1996
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2192578/ https://www.ncbi.nlm.nih.gov/pubmed/8642314

Ejemplares similares

Thymic origin of embryonic intestinal gamma/delta T cells
Publicado: (1993)

Abnormal thymic development, impaired immune function and gamma delta T cell lymphomas in a TL transgenic mouse strain
Publicado: (1991)

Phenotypic and functional analysis of positive selection in the gamma/delta T cell lineage
Publicado: (1993)

Cortical Thymocytes Along With Their Selecting Ligands Are Required for the Further Thymic Maturation of NKT Cells in Mice
por: Klibi, Jihene, et al.
Publicado: (2020)

Differential Requirement for Mesenchyme in the Proliferation and Maturation of Thymic Epithelial Progenitors
por: Jenkinson, William E., et al.
Publicado: (2003)

T cell receptor-mediated signaling events in CD4+CD8+ thymocytes undergoing thymic selection: requirement of calcineurin activation for thymic positive selection but not negative selection
Publicado: (1995)

lambda 5, but not mu, is required for B cell maturation in a unique gamma 2b transgenic mouse line
Publicado: (1995)

Evidence that the T cell antigen receptor may not be involved in cytotoxicity mediated by gamma/delta and alpha/beta thymic cell lines
Publicado: (1987)

Early Steps of a Thymic Tumor in SV40 Transgenic Mice: Hyperplasia of Medullary Epithelial Cells and Increased Mature Thymocyte Numbers Disturb Thymic Export
por: Nabarra, Bernadette, et al.
Publicado: (2002)

Positive and Negative Selection in the Thymus and the Thymic Paradox
por: Reza, Julie N., et al.
Publicado: (1998)

Maturation and migration of murine CD4 single positive thymocytes and thymic emigrants
por: Xu, Xi, et al.
Publicado: (2014)

Transgenic mice demonstrate that epithelial homing of gamma/delta T cells is determined by cell lineages independent of T cell receptor specificity
Publicado: (1990)

NUCLEOLAR MORPHOLOGY AND MATURATION OF THYMIC LYMPHOCYTES
por: Potmesil, Milan, et al.
Publicado: (1972)

Mathematical and numerical methods for the nonlinear hyperbolic propagation problem delta$^{2}$GAMMA/delta.t$^{2}$ = (delta/delta.z)((delta.GAMMA(delta.t)(delta.GAMMA/delta.z)): a preliminary treatment of collective space
por: Funk, U N, et al.
Publicado: (1982)

Delta-like 4 is indispensable in thymic environment specific for T cell development
por: Hozumi, Katsuto, et al.
Publicado: (2008)

An Adult Thymic Stromal-Cell Suspension Model for in Vitro Positive Selection
por: Chidgey, Ann P., et al.
Publicado: (1998)

Selective involution of thymic medulla by cyclosporine A with a decrease of mature thymic epithelia, XCR1(+) dendritic cells, and epithelium-free areas containing Foxp3(+) thymic regulatory T cells
por: Sawanobori, Yasushi, et al.
Publicado: (2021)

Evidence for clonal selection of gamma/delta T cells in response to a human pathogen
Publicado: (1991)

Thymic selection and cell division
Publicado: (1995)

FUNCTIONAL MATURATION OF THYMIC LYMPHOCYTE POPULATIONS IN VITRO
por: Mosier, Donald E., et al.
Publicado: (1972)

Post-thymic T lymphocyte maturation during ontogenesis
Publicado: (1981)

Thymic exosomes promote the final maturation of thymocytes
por: Lundberg, Vanja, et al.
Publicado: (2016)

Peptide-MHC heterodimers show that thymic positive selection requires a more restricted set of self-peptides than negative selection
por: Juang, Jeremy, et al.
Publicado: (2010)

Studies on T cell maturation on defined thymic stromal cell populations in vitro
Publicado: (1992)

Growth of epithelial cells in the thymic medulla is under the control of mature T cells
Publicado: (1992)

A role for interleukin 4 in the differentiation of mature T cell receptor gamma/delta + cells from human intrathymic T cell precursors
Publicado: (1990)

Post-Aire Maturation of Thymic Medullary Epithelial Cells Involves Selective Expression of Keratinocyte-Specific Autoantigens
por: Wang, Xiaoping, et al.
Publicado: (2012)

Control of Intra-Thymic αβ T Cell Selection and Maturation by H3K27 Methylation and Demethylation
por: Bosselut, Rémy
Publicado: (2019)

Selective activation of gamma/delta + T cell clones by single anti-CD2 antibodies
Publicado: (1991)

T cell receptor gamma/delta chain diversity
Publicado: (1988)

Thymic selection and adaptability of cytotoxic T lymphocyte responses in transgenic mice expressing a viral protein in the thymus
Publicado: (1994)

Requirement for p56lck tyrosine kinase activation in T cell receptor- mediated thymic selection
Publicado: (1996)

Current experimental status of $ \Delta \Gamma$ and $ \Delta m$
por: Schiller, Manuel Tobias
Publicado: (2018)

THYMUS CELL MATURATION : STUDIES ON THE ORIGIN OF CORTISONE-RESISTANT THYMIC LYMPHOCYTES
por: Weissman, Irving L.
Publicado: (1973)

T cell self-reactivity during thymic development dictates the timing of positive selection
por: Lutes, Lydia K, et al.
Publicado: (2021)

Established Thymic Epithelial Progenitor/Stem Cell-Like Cell Lines Differentiate into Mature Thymic Epithelial Cells and Support T Cell Development
por: Chen, Pengfei, et al.
Publicado: (2013)

Tolerance of T cell receptor gamma/delta cells in the intestine
Publicado: (1993)

A measurement of $\Delta \Gamma_{s}$
por: Aaij, Roel, et al.
Publicado: (2023)

Perforins Expression by Cutaneous Gamma Delta T Cells
por: O'Neill, Katelyn, et al.
Publicado: (2020)

Gamma Delta T Cells and Their Pathogenic Role in Psoriasis
por: Qi, Cong, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_1ufc84k1hh8tp7mhiumkb3pfnc