Cargando…

Protection from anti-TCR/CD3-induced apoptosis in immature thymocytes by a signal through thymic shared antigen-1/stem cell antigen-2

During T cell development in the thymus, the expression of thymic shared antigen-1 (TSA-1)/stem cell antigen-2 (Sca-2), a glycosylphosphatidylinositol (GPI)-anchored differentiation antigen, is developmentally regulated. The expression level of TSA-1 is the highest in most immature CD4- CD8- thymocy...

Descripción completa

Detalles Bibliográficos
Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 1996
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2192583/ https://www.ncbi.nlm.nih.gov/pubmed/8642345

Ejemplares similares

Thymocytes trigger self-antigen-controlling pathways in immature medullary thymic epithelial stages
por: Lopes, Noella, et al.
Publicado: (2022)

Antigen Recognition By Autoreactive Cd4(+) Thymocytes Drives Homeostasis Of The Thymic Medulla
por: Irla, Magali, et al.
Publicado: (2012)

The Molecular Signature Underlying the Thymic Migration and Maturation of TCRαβ(+)CD4(+)CD8(-) Thymocytes
por: Teng, Fei, et al.
Publicado: (2011)

Immature CD4(+)CD8(+) Thymocytes Are Preferentially Infected by Measles Virus in Human Thymic Organ Cultures
por: Okamoto, Yukari, et al.
Publicado: (2012)

In vitro maturation of immature thymocytes into immunocompetent T cells in the absence of direct thymic influence
por: Irle, C, et al.
Publicado: (1978)

Developmentally regulated expression of CD3 components independent of clonotypic T cell antigen receptor complexes on immature thymocytes
Publicado: (1994)

Selection of Thymocytes Expressing Transgenic TCR Specific for a Minor Histocompatibility Antigen, H60
por: Ju, Ji-Min, et al.
Publicado: (2015)

Thymic Atrophy and Apoptosis of CD4(+)CD8(+) Thymocytes in the Cuprizone Model of Multiple Sclerosis
por: Solti, Izabella, et al.
Publicado: (2015)

Anaplastic large cell lymphoma arises in thymocytes and requires transient TCR expression for thymic egress
por: Malcolm, Tim I. M., et al.
Publicado: (2016)

An anti-DEC-205 monoclonal antibody stimulates binding of thymocytes to rat thymic dendritic cells and promotes apoptosis of thymocytes
por: Majstorović, Ivana, et al.
Publicado: (2014)

Cross-Linking the TCR Complex Induces Apoptosis in CD4(+)8(+) Thymocytes in the Presence of Cyclosporin A
por: Poetschke, Heather L., et al.
Publicado: (1996)

Gene transcription in differentiating immature T cell receptor(neg) thymocytes resembles antigen-activated mature T cells
Publicado: (1993)

Early molecular events induced by T cell receptor (TCR) signaling in immature CD4+ CD8+ thymocytes: increased synthesis of TCR-alpha protein is an early response to TCR signaling that compensates for TCR-alpha instability, improves TCR assembly, and parallels other indicators of positive selection
Publicado: (1995)

Commitment of Immature CD4(+)8(+) Thymocytes to the CD4 Lineage Requires CD3 Signaling but Does Not Require Expression of Clonotypic T Cell Receptor (TCR) Chains
por: Suzuki, Harumi, et al.
Publicado: (1997)

An intermediate cell in thymocyte differentiation that expresses CD8 but not CD4 antigen
Publicado: (1987)

Shorter TCR β-Chains Are Highly Enriched During Thymic Selection and Antigen-Driven Selection
por: Hou, Xianliang, et al.
Publicado: (2019)

The Programmed Cell Death of an Immature Thymocyte Cell Line Transgenic for an αβ TCR and the c-myc Proto-Oncogene
por: Murdjeva, Marianna, et al.
Publicado: (1995)

Murine T-Lymphomas Corresponding to the Immature CD4(-)8(+) Thymocyte Subset
por: Richie, Ellen R., et al.
Publicado: (1991)

T Cell Receptor (TCR)-induced Death of Immature CD4(+)CD8(+) Thymocytes by Two Distinct Mechanisms Differing in Their Requirement for CD28 Costimulation: Implications for Negative Selection in the Thymus
por: Punt, Jennifer A., et al.
Publicado: (1997)

The JNK Pathway Regulates the In Vivo Deletion of Immature CD4(+)CD8(+) Thymocytes
por: Rincón, Mercedes, et al.
Publicado: (1998)

A new differentiation antigen (FT-1) shared with fetal thymocytes and leukemic cells in the mouse
Publicado: (1984)

Selective apoptosis of CD4+CD8+ thymocytes by the anti-Fas antibody
Publicado: (1995)

Maturation and migration of murine CD4 single positive thymocytes and thymic emigrants
por: Xu, Xi, et al.
Publicado: (2014)

Tolerance in TCR/Cognate Antigen Double-Transgenic Mice Mediated by Incomplete Thymic Deletion and Peripheral Receptor Downregulation
por: Mamalaki, Clio, et al.
Publicado: (1995)

Increased TCR signal strength in DN thymocytes promotes development of gut TCRαβ((+))CD8αα((+)) intraepithelial lymphocytes
por: Grandjean, Capucine L., et al.
Publicado: (2017)

Thymic exosomes promote the final maturation of thymocytes
por: Lundberg, Vanja, et al.
Publicado: (2016)

Regulation of T cell receptor expression in immature CD4+CD8+ thymocytes by p56lck tyrosine kinase: basis for differential signaling by CD4 and CD8 in immature thymocytes expressing both coreceptor molecules
Publicado: (1993)

Preferential expression of fibronectin receptors on immature thymocytes
Publicado: (1988)

Structure of the T cell antigen receptor (TCR): two CD3 epsilon subunits in a functional TCR/CD3 complex
Publicado: (1991)

Stoichiometry of the T cell antigen receptor (TCR) complex: each TCR/CD3 complex contains one TCR alpha, one TCR beta, and two CD3 epsilon chains
Publicado: (1994)

TCR repertoire profiling revealed antigen-driven CD8+ T cell clonal groups shared in synovial fluid of patients with spondyloarthritis
por: Komech, Ekaterina A., et al.
Publicado: (2022)

Complete Diabetes Protection Despite Delayed Thymic Tolerance in NOD8.3 TCR Transgenic Mice Due to Antigen-Induced Extrathymic Deletion of T Cells
por: Krishnamurthy, Balasubramanian, et al.
Publicado: (2012)

The thymic medulla is required for Foxp3(+) regulatory but not conventional CD4(+) thymocyte development
por: Cowan, Jennifer E., et al.
Publicado: (2013)

Identification of CD8 as a peanut agglutinin (PNA) receptor molecule on immature thymocytes
Publicado: (1996)

c-Myb primes CD4(+)CD8(+) immature thymocytes for selection into the iNKT lineage
por: Hu, Taishan, et al.
Publicado: (2010)

Domains of the TCR beta-chain required for early thymocyte development
Publicado: (1996)

Effects of sex steroids on thymic epithelium and thymocyte development
por: Taves, Matthew D., et al.
Publicado: (2022)

Human Innate Mycobacterium tuberculosis–Reactive αβTCR(+) Thymocytes
por: Gold, Marielle C, et al.
Publicado: (2008)

Galectin-1, an Endogenous Lectin Produced by Thymic Epithelial Cells, Induces Apoptosis of Human Thymocytes
por: Perillo, Nancy L., et al.
Publicado: (1997)

A specific biosynthetic marker for immature thymic lymphoblasts. Active synthesis of thymus-leukemia antigen restricted to proliferating cells
por: Rothenberg, E
Publicado: (1982)

Cannot write session to /tmp/vufind_sessions/sess_htsdf2ojuug5njrbv7jbganc5d