Cargando…

A Human Immunoglobulin (Ig)A Cα3 Domain Motif Directs Polymeric Ig Receptor–mediated Secretion

Polymeric immunoglobulins provide immunological protection at mucosal surfaces to which they are specifically transported by the polymeric immunoglobulin receptor (pIgR). Using a panel of human IgA1/IgG1 constant region “domain swap” mutants, the binding site for the pIgR on dimeric IgA (dIgA) was l...

Descripción completa

Detalles Bibliográficos
Autores principales: Hexham, J. Mark, White, Kendra D., Carayannopoulos, Leonidas N., Mandecki, Wlodeck, Brisette, Renee, Yang, Yih-Sheng, Capra, J. Donald
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1999
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2192928/
https://www.ncbi.nlm.nih.gov/pubmed/9989991