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Endotoxin-tolerant Mice Have Mutations in Toll-like Receptor 4 (Tlr4)

Bacterial lipopolysaccharide (LPS) provokes a vigorous, generalized proinflammatory state in the infected host. Genetic regulation of this response has been localized to the Lps locus on mouse chromosome 4, through study of the C3H/HeJ and C57BL/10ScCr inbred strains. Both C3H/HeJ and C57BL/10ScCr m...

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Detalles Bibliográficos
Autores principales:	Qureshi, Salman T., Larivière, Line, Leveque, Gary, Clermont, Sophie, Moore, Karen J., Gros, Philippe, Malo, Danielle
Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 1999
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2192941/ https://www.ncbi.nlm.nih.gov/pubmed/9989976

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