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Human Herpesvirus 6 (HHV-6) Causes Severe Thymocyte Depletion in SCID-hu Thy/Liv Mice
Human herpesvirus 6 (HHV-6) is a potentially immunosuppressive agent that may act as a cofactor in the progression of AIDS. Here, we describe the first small animal model of HHV-6 infection. HHV-6 subgroup A, strain GS, efficiently infected the human thymic tissue implanted in SCID-hu Thy/Liv mice,...
Autores principales: | Gobbi, Alberto, Stoddart, Cheryl A., Malnati, Mauro S., Locatelli, Giuseppe, Santoro, Fabio, Abbey, Nancy W., Bare, Christopher, Linquist-Stepps, Valerie, Moreno, Mary Beth, Herndier, Brian G., Lusso, Paolo, McCune, Joseph M. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
1999
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2192958/ https://www.ncbi.nlm.nih.gov/pubmed/10377191 |
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