Cargando…
Mitochondrial Release of Caspase-2 and -9 during the Apoptotic Process
The barrier function of mitochondrial membranes is perturbed early during the apoptotic process. Here we show that the mitochondria contain a caspase-like enzymatic activity cleaving the caspase substrate Z-VAD.afc, in addition to three biological activities previously suggested to participate in th...
Autores principales: | Susin, Santos A., Lorenzo, Hans K., Zamzami, Naoufal, Marzo, Isabel, Brenner, Catherine, Larochette, Nathanael, Prévost, Marie-Christine, Alzari, Pedro M., Kroemer, Guido |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
1999
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2192979/ https://www.ncbi.nlm.nih.gov/pubmed/9892620 |
Ejemplares similares
-
The Permeability Transition Pore Complex: A Target for Apoptosis Regulation by Caspases and Bcl-2–related Proteins
por: Marzo, Isabel, et al.
Publicado: (1998) -
Apoptosis Control in Syncytia Induced by the HIV Type 1–Envelope Glycoprotein Complex: Role of Mitochondria and Caspases
por: Ferri, Karine F., et al.
Publicado: (2000) -
The Central Executioner of Apoptosis: Multiple Connections between Protease Activation and Mitochondria in Fas/APO-1/CD95- and Ceramide-induced Apoptosis
por: Susin, Santos A., et al.
Publicado: (1997) -
Two Distinct Pathways Leading to Nuclear Apoptosis
por: Susin, Santos A., et al.
Publicado: (2000) -
Evaluation Expression of the Caspase-3 and Caspase-9 Apoptotic Genes in Schizophrenia Patients
por: Dirican, Ebubekir, et al.
Publicado: (2023)