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Structural Evidence of T Cell Xeno-reactivity in the Absence of Molecular Mimicry
The T cell receptor (TCR), from a xeno-reactive murine cytotoxic T lymphocyte clone AHIII12.2, recognizes murine H-2D(b) complexed with peptide p1027 (FAPGVFPYM), as well as human HLA-A2.1 complexed with peptide p1049 (ALWGFFPVL). A commonly proposed model (the molecular mimicry model) used to expla...
Autores principales: | Zhao, Rui, Loftus, Douglas J., Appella, Ettore, Collins, Edward J. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
1999
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2192988/ https://www.ncbi.nlm.nih.gov/pubmed/9892618 |
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