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Structural Evidence of  T Cell Xeno-reactivity in the Absence of Molecular Mimicry

The T cell receptor (TCR), from a xeno-reactive murine cytotoxic T lymphocyte clone AHIII12.2, recognizes murine H-2D(b) complexed with peptide p1027 (FAPGVFPYM), as well as human HLA-A2.1 complexed with peptide p1049 (ALWGFFPVL). A commonly proposed model (the molecular mimicry model) used to expla...

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Detalles Bibliográficos
Autores principales: Zhao, Rui, Loftus, Douglas J., Appella, Ettore, Collins, Edward J.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1999
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2192988/
https://www.ncbi.nlm.nih.gov/pubmed/9892618

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