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Altered Ligands Reveal Limited Plasticity in the T Cell Response to a Pathogenic Epitope

Experimental leishmaniasis offers a well characterized model of T helper type 1 cell (Th1)-mediated control of infection by an intracellular organism. Susceptible BALB/c mice aberrantly develop Th2 cells in response to infection and are unable to control parasite dissemination. The early CD4(+) T ce...

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Detalles Bibliográficos
Autores principales: Pingel, Sabine, Launois, Pascal, Fowell, Deborah J., Turck, Christoph W., Southwood, Scott, Sette, Alessandro, Glaichenhaus, Nicolas, Louis, Jacques A., Locksley, Richard M.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1999
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193001/
https://www.ncbi.nlm.nih.gov/pubmed/10190902