Cargando…

Altered Ligands Reveal Limited Plasticity in the T Cell Response to a Pathogenic Epitope

Experimental leishmaniasis offers a well characterized model of T helper type 1 cell (Th1)-mediated control of infection by an intracellular organism. Susceptible BALB/c mice aberrantly develop Th2 cells in response to infection and are unable to control parasite dissemination. The early CD4(+) T ce...

Descripción completa

Detalles Bibliográficos
Autores principales:	Pingel, Sabine, Launois, Pascal, Fowell, Deborah J., Turck, Christoph W., Southwood, Scott, Sette, Alessandro, Glaichenhaus, Nicolas, Louis, Jacques A., Locksley, Richard M.
Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 1999
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193001/ https://www.ncbi.nlm.nih.gov/pubmed/10190902

Ejemplares similares

Microbial Epitopes Act as Altered Peptide Ligands to Prevent Experimental Autoimmune Encephalomyelitis
por: Ruiz, Pedro J., et al.
Publicado: (1999)

Predicting population coverage of T-cell epitope-based diagnostics and vaccines
por: Bui, Huynh-Hoa, et al.
Publicado: (2006)

Allele-Specific Thresholds of Eluted Ligands for T-Cell Epitope Prediction
por: Reardon, Brian, et al.
Publicado: (2021)

IL-4 Attenuates Th1-Associated Chemokine Expression and Th1 Trafficking to Inflamed Tissues and Limits Pathogen Clearance
por: Lazarski, Christopher A., et al.
Publicado: (2013)

Interferon γ Derived from CD4(+) T Cells Is Sufficient to Mediate T Helper Cell Type 1 Development
por: Wakil, Adil E., et al.
Publicado: (1998)

Structural Features of Peptide Analogs of Human Histocompatibility Leukocyte Antigen Class I Epitopes That Are More Potent and Immunogenic than Wild-Type Peptide
por: Tangri, Shabnam, et al.
Publicado: (2001)

Nine lives: plasticity among T helper cell subsets
por: Locksley, Richard M.
Publicado: (2009)

Epitope Specific Antibodies and T Cell Receptors in the Immune Epitope Database
por: Mahajan, Swapnil, et al.
Publicado: (2018)

Development of an epitope conservancy analysis tool to facilitate the design of epitope-based diagnostics and vaccines
por: Bui, Huynh-Hoa, et al.
Publicado: (2007)

Human Norovirus Epitope D Plasticity Allows Escape from Antibody Immunity without Loss of Capacity for Binding Cellular Ligands
por: Lindesmith, Lisa C., et al.
Publicado: (2019)

The Immune Epitope Database and Analysis Resource in Epitope Discovery and Synthetic Vaccine Design
por: Fleri, Ward, et al.
Publicado: (2017)

Integrating epitope data into the emerging web of biomedical knowledge resources
por: Peters, Bjoern, et al.
Publicado: (2007)

Ontology Development for the Immune Epitope Database
por: Greenbaum, Jason A., et al.
Publicado: (2009)

Navigating diabetes-related immune epitope data: resources and tools provided by the Immune Epitope Database (IEDB)
por: Vaughan, Kerrie, et al.
Publicado: (2013)

Design and utilization of epitope-based databases and predictive tools
por: Salimi, Nima, et al.
Publicado: (2010)

Automating document classification for the Immune Epitope Database
por: Wang, Peng, et al.
Publicado: (2007)

Better living through ontologies at the Immune Epitope Database
por: Vita, Randi, et al.
Publicado: (2017)

The immune epitope database (IEDB) 3.0
por: Vita, Randi, et al.
Publicado: (2014)

Pathogenic epitopes, heterologous immunity and vaccine design
por: Welsh, Raymond M., et al.
Publicado: (2007)

Limiting plastic waste in dry eye practice for environmental sustainability
por: Govindasamy, Gayathri, et al.
Publicado: (2022)

Toll-like receptor 2 on inflammatory monocytes induces type I interferon in response to viral but not bacterial ligands
por: Barbalat, Roman, et al.
Publicado: (2009)

A Comparison of Epitope Repertoires Associated with Myasthenia Gravis in Humans and Nonhuman Hosts
por: Vaughan, Kerrie, et al.
Publicado: (2012)

The Immune Epitope Database: How Data Are Entered and Retrieved
por: Fleri, Ward, et al.
Publicado: (2017)

Classification of the Universe of Immune Epitope Literature: Representation and Knowledge Gaps
por: Davies, Vince, et al.
Publicado: (2009)

The Immune Epitope Database 2.0
por: Vita, Randi, et al.
Publicado: (2010)

Altered Immune Responses in Interleukin 10 Transgenic Mice
por: Hagenbaugh, Amy, et al.
Publicado: (1997)

P17-24. Interfering overlapping epitopes contribute to the subdominance of an HLA-A2-restricted HIV Gag-specific epitope
por: Kan-Mitchell, J, et al.
Publicado: (2009)

Microbiota epitope similarity either dampens or enhances the immunogenicity of disease-associated antigenic epitopes
por: Carrasco Pro, Sebastian, et al.
Publicado: (2018)

Conformational selection of allergen-antibody complexes—surface plasticity of paratopes and epitopes
por: Fernández-Quintero, Monica L, et al.
Publicado: (2019)

Automatic Generation of Validated Specific Epitope Sets
por: Carrasco Pro, Sebastian, et al.
Publicado: (2015)

Conservancy of mAb Epitopes in Ebolavirus Glycoproteins of Previous and 2014 Outbreaks
por: Ponomarenko, Julia, et al.
Publicado: (2014)

IMMUNOCAT—A Data Management System for Epitope Mapping Studies
por: Chung, Jo L., et al.
Publicado: (2010)

A1 is induced by pathogen ligands to limit myeloid cell death and NLRP3 inflammasome activation
por: Speir, Mary, et al.
Publicado: (2023)

Comparative Multi-Epitope-Ligand-Cartography reveals essential immunological alterations in Barrett's metaplasia and esophageal adenocarcinoma
por: Berndt, Uta, et al.
Publicado: (2010)

The Cancer Epitope Database and Analysis Resource (CEDAR)
por: Koşaloğlu-Yalçın, Zeynep, et al.
Publicado: (2022)

In silico identification of common epitopes from pathogenic mycobacteria
por: de la Caridad Addine Ramírez, Bárbara, et al.
Publicado: (2013)

The Immune Epitope Database and Analysis Resource Program 2003–2018: reflections and outlook
por: Martini, Sheridan, et al.
Publicado: (2019)

Constraints on the evolution of phenotypic plasticity: limits and costs of phenotype and plasticity
por: Murren, C J, et al.
Publicado: (2015)

Plasticity of PDZ domains in ligand recognition and signaling
por: Ivarsson, Ylva
Publicado: (2012)

IEDB‐3D 2.0: Structural data analysis within the Immune Epitope Database
por: Mendes, Marcus, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_kshpiei3rqfdpd0495dp5jtclj