Cytotoxic T Lymphocyte–associated Antigen 4 (CTLA-4) Can Regulate Dendritic Cell–induced Activation and Cytotoxicity of CD8(+) T Cells Independently of CD4(+)T Cell Help

The mechanisms that regulate the strength and duration of CD8(+) cytotoxic T cell activity determine the effectiveness of an antitumor immune response. To better understand the antitumor effects of anti-cytotoxic T lymphocyte–associated antigen 4 (CTLA-4) antibody treatment, we analyzed the effect o...

Descripción completa

Detalles Bibliográficos
Autores principales: McCoy, Kathy D., Hermans, Ian F., Henry Fraser, J., Le Gros, Graham, Ronchese, Franca
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1999
Materias:
Brief Definitive Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193004/
https://www.ncbi.nlm.nih.gov/pubmed/10190907

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193004/
https://www.ncbi.nlm.nih.gov/pubmed/10190907

Ejemplares similares