Defective Interleukin (IL)-18–mediated Natural Killer and T Helper Cell Type 1 Responses in IL-1 Receptor–associated Kinase (IRAK)-deficient Mice

Interleukin (IL)-18 is functionally similar to IL-12 in mediating T helper cell type 1 (Th1) response and natural killer (NK) cell activity but is related to IL-1 in protein structure and signaling, including recruitment of IL-1 receptor–associated kinase (IRAK) to the receptor and activation of c-J...

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Autores principales: Kanakaraj, Palanisamy, Ngo, Karen, Wu, Ying, Angulo, Ana, Ghazal, Peter, Harris, Crafford A., Siekierka, John J., Peterson, Per A., Fung-Leung, Wai-Ping
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1999
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2193007/
https://www.ncbi.nlm.nih.gov/pubmed/10190904

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